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Frequency not reported: Nail disorders, skin discoloration, leukocytoclastic vasculitisThe tricyclic antidepressants and bupropion (Wellbutrin) are not FDA-approved for treatment of ADHD but are often used off-label. The tricyclic antidepressants affect levels of norepinephrine while bupropion affects levels of both norepinephrine and dopamine. Imipramine and desipramine are the most commonly used tricyclic antidepressants. However nortriptyline is also effective.Antidepressants

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DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, s, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: carbonic anhydrase inhibitors (such as acetazolamide). Other medications can affect the removal of zonisamide from your body, which may affect how zonisamide works. Examples include other medications to treat seizures (such as carbamazepine, phenobarbital, phenytoin, primidone), rifamycins (such as rifabutin), St. John's wort, among others. Your doctor may need to adjust your dose of zonisamide if you are on these medications. Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Using this medicine does not protect you or your partner against HIV infection (the virus that causes AIDS) or other sexually transmitted diseases.kidney or liver diseasesigns of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, unusual weakness;Common (1% to 10%): Nervousness (included agitation/hyperactive), abnormal dreams, severe depression, hallucinations

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stuffy or runny noseVery common (10% or more): Diarrhea (up to 14%)Patients treated with Enbrel are at increased risk for developing serious infections that may lead to hospitalization or death [see WARNINGS AND PRECAUTIONS and ADVERSE REACTIONS]. Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids.

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