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Dosage Adjustments Due to Drug Interactions viagra half life other medicines or treatments for EDIf you are taking sildenafil to treat PAH, follow your doctor's directions and the guidelines in this paragraph. You will probably take sildenafil three times a day with or without food. Take sildenafil at around the same times every day, and space your doses about 4 to 6 hours apart.TheStreet or Hotmail). This in turn will alter the economy of the

What happens if I miss a dose? cialis 30 day free trial In order to get a normal healthy erection, you need to have enough of a substance called cGMP (cyclic guanosine monophosphate) in the body of your penis. This substance binds with nitric oxide causing penile muscles to relax. This, in its turn, allows more blood to enter the penis and gives you an erection. When you are suffering from erectile dysfunction, you have increased levels of PDE5 enzyme in your body. This enzyme disintegrates cGMP and prevents you from getting erections the way you are used to. Viagra inhibits PDE5 and keeps the level of cGMP in your system high restoring your normal sexual function.

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In clinical studies, Viagra was assessed for its effect on the ability of men with erectile dysfunction (ED) to engage in sexual activity and in many cases specifically on the ability to achieve and maintain an erection sufficient for satisfactory sexual activity. Viagra was evaluated primarily at doses of 25 mg, 50 mg and 100 mg in 21 randomized, double-blind, placebo-controlled trials of up to 6 months in duration, using a variety of study designs (fixed dose, titration, parallel, crossover). Viagra was administered to more than 3,000 patients aged 19 to 87 years, with ED of various etiologies (organic, psychogenic, mixed) with a mean duration of 5 years. Viagra demonstrated statistically significant improvement compared to placebo in all 21 studies. The studies that established benefit demonstrated improvements in success rates for sexual intercourse compared with placebo. does viagra work

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